人気の注目キーワード::HIV

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作成者：drrufusrajadurai
タイトル：HIV Replication 3D Medical Animation
タグ： hiv replication medical animation 3d aids virus dr rufus rajadurai ccr5 cxcr4 cd4
説明：it is a very excellent animation which explains the hiv replication very clearly. For free download of this video please visit my webpage http://rufusrajadurai.wetpaint.com/page/Download And other 3D animation videos visit http://rufusrajadurai.wetpaint.com/page/3D+Medical+Animation+Library Regards, Dr.Rufus The Lyrics of this video is here Targeting HIV replication The replication of HIV 1 is a multi-stage process. Each step is crucial to successful replication and is therefore a potential target of antiretroviral drugs. Step one is the infection of a suitable host-cell, such as a CD4-positive T-lymphocyte. Entry of HIV into the cell requires the presence of certain receptors on the cell surface, CD4 -- receptors and co-receptors such as CCR5 or CXCR4. These receptors interact with protein-complexes, which are embedded in the viral envelope. These complexes are composed of two glycoproteins: an extracellular gp 120 and a transmembrane gp 41 When HIV approaches the target cell gp120 binds to the CD4-receptors. This process is termed attachment. It promotes further binding to a co-receptor. Co-receptor binding results in a conformational change in gp120. This allows gp41 to unfold and insert its hydrophobic terminus into the cell membrane. Gp 41 then folds back on itself. This draws the virus towards the cell and facilitates the fusion of their membranes. The viral nucleocapsid enters the host cell and breaks open releasing two viral RNA-strands and 3 essential replication enzymes: Integrase, Protease and Reverse Transcriptase. Reverse Transcriptase begins the reverse transcription of viral RNA. It has two catalytic domains: The Ribonuclease-H active site And the polymerase active site Here single stranded viral RNA is transcribed into an RNA-DNA double helix. Ribonuclease- H breaks down the RNA. The polymerase then completes the remaining DNA-strand to form a DNA -- double helix. Now Integrase goes into action. It cleaves a dinucleotide from each 3-prime end of the DNA creating two sticky ends. Integrase then transfers the DNA into the cell nucleus and facilitates its integration into the host cell genome. The host cell genome now contains the genetic information of HIV. Activation of the cell induces transcription of proviral DNA into messenger RNA. The viral messenger RNA migrates into the cytoplasm where building blocks for a new virus are synthesised. Some of them have to be processed by the viral protease. Protease cleaves longer proteins into smaller core proteins. This step is crucial to create an infectious virus. Two viral RNA-strands and the replication enzymes then come together and core proteins assemble around them forming the capsid. This immature particle leaves the cell acquiring a new envelope of host and viral proteins. The virus matures and becomes ready to infect other cells. HIV replicates billions of times per day destroying the hosts` immune cells and eventually causing disease progression. Drugs which interfere with the key steps of viral replication can stop this fatal process. Entry into the host cell can be blocked by fusion inhibitors for example. Inhibition of reverse transcriptase by nucleoside inhibitors or by non-nucleoside Reverse Transcriptase- inhibitors is part of standard antiretroviral regimens. The action of Integrase can be blocked. Protease inhibitors are also part of standard antiretroviral therapy. Each blocked step in viral replication is a step towards better control of HIV disease. Script, Storyboard, Art Direction by: Frank Schauder, MD Animation: MACKEVISION Publicity: Dr.Rufus Rajadurai.M.D.,D.DENS.,

作成者：AIDSvideos
タイトル：Did I Just Contract HIV? Symptoms of Primary HIV Infection
タグ： hiv replication medical animation 3d aids virus dr rufus rajadurai ccr5 cxcr4 cd4 hiv aids primary infection symptoms test fever rash lymph nodes fatigue nausea vomiting sore throat mouth genital joint
説明：It's sometimes possible to recognize when you've recently contracted HIV from signs and symptoms such as fever, rash, or swollen lymph nodes. This video will teach you how to recognize signs and symptoms of primary HIV infection that are experienced by between 40 and 90% of individuals after they are first infected with HIV. Primary HIV infection occurs during the first few weeks or months after a person first becomes infected with HIV. Symptoms include rash and/or fevers, possibly in combination with one or more of the following symptoms: malaise (which is a general feeling of weakness, discomfort, and fatigue), loss of appetite, weight loss, a sore throat, sores in the mouth, joint or muscle pain, swollen lymph nodes, diarrhea, fatigue, night sweats, nausea and vomiting, headache, or genital sores. The symptoms usually last from seven to ten days, and rarely more than two weeks. There is an incubation period of a few days to a few weeks between when the person was exposed to HIV and when the symptoms begin. If you have any of these symptoms and think there's even the slightest chance you might have been exposed to HIV, such as through recent sexual activity or sharing a needle, even with someone who you believe is HIV negative, you should see a doctor and ask to be tested for HIV. When you go to the doctor with any of these symptoms, it's very important to mention any risk factors you may have for HIV so they could test you. If you have ever had unprotected sex, even once, have used injection drugs, or think you might be experiencing primary HIV infection, make sure to tell your doctor. Visit http://www.GlobalLifeworks.org and http://AIDSvideos.org to learn more. [Do you want to help prevent the spread of HIV/AIDS? Are you fluent in a language other than English? Then volunteer to translate this video into another language! Click http://AIDSvideos.org/translate.shtml to to learn how you can help!!!]

作成者：auxv
タイトル：HIV virus
タグ： hiv replication medical animation 3d aids virus dr rufus rajadurai ccr5 cxcr4 cd4 hiv aids primary infection symptoms test fever rash lymph nodes fatigue nausea vomiting sore throat mouth genital joint HIV Virus AIDS
説明：Process of HIV virus cell entry.

作成者：illumistream
タイトル：When HIV Becomes AIDS (HIV #2)
タグ： hiv replication medical animation 3d aids virus dr rufus rajadurai ccr5 cxcr4 cd4 hiv aids primary infection symptoms test fever rash lymph nodes fatigue nausea vomiting sore throat mouth genital joint HIV Virus AIDS hiv aids t-cell opportunistic std cancer sex cmv kaposi's sarcoma non-hodgkin's lymphoma become virus gay sick sexual dr medicine health advice personals video blog dating home condom
説明：HIV and AIDS are not the same thing, but the virus can lead to the disease. Learn how in this video. See more videos on HIV & AIDS: http://www.sexhealthguru.com/index.php?hiv_and_aids-1&YT214AIDS2

作成者：CBS
タイトル：Possible HIV Cure?
タグ： hiv replication medical animation 3d aids virus dr rufus rajadurai ccr5 cxcr4 cd4 hiv aids primary infection symptoms test fever rash lymph nodes fatigue nausea vomiting sore throat mouth genital joint HIV Virus AIDS hiv aids t-cell opportunistic std cancer sex cmv kaposi's sarcoma non-hodgkin's lymphoma become virus gay sick sexual dr medicine health advice personals video blog dating home condom hiv cure houston texas virus discovered lee
説明：Two doctors in Houston, Texas, believe they might have discovered the Achilles heel of the HIV virus. KHOU's Lee McGuire reports.

作成者：bluehorse678
タイトル：HIV/AIDS in Zimbabwe
タグ： hiv replication medical animation 3d aids virus dr rufus rajadurai ccr5 cxcr4 cd4 hiv aids primary infection symptoms test fever rash lymph nodes fatigue nausea vomiting sore throat mouth genital joint HIV Virus AIDS hiv aids t-cell opportunistic std cancer sex cmv kaposi's sarcoma non-hodgkin's lymphoma become virus gay sick sexual dr medicine health advice personals video blog dating home condom hiv cure houston texas virus discovered lee HIV AIDS Zimbabwe Africa Children Casting Crowns Free
説明：this is a video that i did for my english class. I wrote a research paper on the HIV/AIDS crisis in Zimbabwe and to help put my paper into perspective, i made this video to go along with it.